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Previously, several studies had demonstrated that the expression of some important proteins, as well as the activities of certain enzymes was significantly changed after riboflavin deficiency based on immunoblotting analysis or biochemical tests 17,18

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Exenatide (EXE) (2 mg weekly), Dapagliflozin (DAPA) (10 mg daily), Exenatide + Dapagliflozin (2 mg weekly/10 mg daily), Dapagliflozin (10 mg) + Metformin (MET) (2000 mg extended release daily), or Phentermine (7.5 mg)/Topiramate were given to the patients for 24 weeks (46 mg extended release daily)